Recent publications from the Langlois Lab and collaborations

Stoley M, Knudson C, Hartwig S, Pewe L, Meyerholz D, Langlois RA, Harty JT, Varga SM. Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection. PLoS Pathogens 2018 Jan 2;14(1):e1006810. doi: 10.1371/journal.ppat.1006810. eCollection 2018 Jan.


Waring BM, Sjaastad LE, Fiege JK, Fay EJ, Reyes I, Moriarity B, Langlois RA. microRNA based attenuation of influenza virus across susceptible hosts. Journal of Virology. doi: 10.1128/JVI.01741-17  Oct 2017 PMID 29093096


Hamilton JR, Sachs D, Lim JK, Langlois RA, Palese P and Heaton NH. Club cells surviving influenza A virus infection induce temporal nonspecific antiviral immunity. PNAS. March 2016, in press. doi:10.1073/pnas.1522376113


Hemann EA, Sjaastad LE, Langlois RA and Legge KL. Plasmacytoid dendritic cells require direct infection to sustain the pulmonary influenza a virus-specific CD8 T cell response. Journal of Virology. 2015. pii: JVI.02546-15. PMID 26719269


Fiege JK and Langlois RA.  Investigating Influenza A Virus infection:  Tools to track infection and limit tropism. Journal of Virology. 2015. doi: 10.1128/JVI.00462-15  PMID 25855737


Heaton NH*, Langlois RA*, Sachs D, Lim JK, Palese P* and tenOever BR*. Long-term survival of influenza virus infected club cells drives immunopathology. Journal of Experimental Medicine.  doi: 10.1084/jem.20140488. 2014. PMID: 25135297


Backes S, Langlois RA, Schmid S, Shim JV, Sachs D, and tenOever BR. The mammalian response to RNA virus infections is independent of RNAi. Cell Reports. 2014. doi: 10.1016/j.celrep.2014.05.038. PMID: 24953656


Langlois RA*, Albrecht RA*, Kimble B, Sutton T, Shapiro JS, Finch C, Angel M, Chua MA, Gonzalez-Reiche AS, Xu K, Perez D, Garcia-Sastre A, tenOever BR. MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies.  Nature Biotechnology 2013. doi:10.1038/nbt.2666. PMID:23934176


Chua MA, Perez JT, Shmidt S, Langlois RA, tenOever BR. Influenza A Virus Utilizes Suboptimal Splicing to Coordinate the Timing of Infection. Cell Reports. 2013 Jan 15. pii: S2211-1247(12)00454-8. PMID:23333274


Pica N, Langlois RA, Krammer F, Margarine I, and Palese, P. NS1-truncated live attenuated virus vaccine provides robust protection to aged mice from viral challenge. Journal of Virology. 2012 86(19):10293-10301. PMID:22787224


Langlois RA, Varble A, Chua MA, García-Sastre A, and tenOever BR. Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses. PNAS. 2012 Jul 24;109(30):12117-22. PMID:22778433